IN VITRO EVOLUTION IN MICROFLUIDIC SYSTEMS

摘要

PROBLEM TO BE SOLVED: To provide a method for isolating one or more genetic elements encoding a gene product having a desired activity, the method comprising the steps of (a) compartmentalizing genetic elements into microcapsules and (b) sorting the genetic elements which express the gene product having the desired activity; where at least one step is under microfluidic control.SOLUTION: A method for isolating one or more genetic elements encoding a gene product having a desired activity comprises the steps of (a) compartmentalizing genetic elements into microcapsules and (b) sorting the genetic elements which express the gene product having the desired activity; where at least one step is under microfluidic control.SELECTED DRAWING: None