发明名称 COMPOUND WITH (SUBSTITUTED PHENYL)-PROPENAL MOIETY, THEIR DERIVATIVE, BIOLOGICAL ACTIVITY AND USE THEREOF
摘要 PROBLEM TO BE SOLVED: To provide a treating method using a compound useful in treatment or prevention of various medical conditions including androgen-associated conditions.SOLUTION: A pharmaceutical composition for treating a subject suffering from a medical condition associated with androgen receptor comprises a compound represented by Formula IIa or IIb, in which R3, R4, R3' and R4' are each independently H, OH or OCH3; L is carbonyl, alkylene or alkenylene or when Z is not present, alkynyl; Z is H, OH, substituted styrenyl, aromatic ring, cycloalkyl, -COR1, -CONR1R2 or -CX3; R1 and R2 are each independently H, CH3 or C2H5 or Z is not present; X is a halogen atom selected from F, Cl and Br.SELECTED DRAWING: None
申请公布号 JP2016065068(A) 申请公布日期 2016.04.28
申请号 JP20150212420 申请日期 2015.10.29
申请人 ALLIANZ PHARMASCIENCE LTD 发明人 SHIH CHARLES C Y;SHI QIAN;WANG HUI-KANG;SU CHING-YUAN
分类号 A61K31/12;A61K8/35;A61K8/42;A61K31/122;A61K31/165;A61P1/16;A61P5/28;A61P13/08;A61P13/10;A61P15/00;A61P17/02;A61P17/10;A61P17/14;A61P21/00;A61P29/00;A61P35/00;A61P43/00;A61Q7/00;A61Q7/02;A61Q19/00;C07C49/255;C07C235/78 主分类号 A61K31/12
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