发明名称 |
CRYSTALLINE FORMS OF THERAPEUTIC COMPOUNDS AND USES THEREOF |
摘要 |
Described herein are certain crystalline forms of Compound 3, as well as pharmaceutical compositions employing the crystalline forms. Also provided are particles (e.g., nanoparticles) comprising such crystalline forms or pharmaceutical compositions. In certain examples, the particles are mucus penetrating particles (MPPs). The present invention further relates to methods of treating or preventing diseases using crystalline forms or pharmaceutical compositions. |
申请公布号 |
US2016115176(A1) |
申请公布日期 |
2016.04.28 |
申请号 |
US201514981105 |
申请日期 |
2015.12.28 |
申请人 |
Kala Pharmaceuticals, Inc. |
发明人 |
Enlow Elizabeth;Nguyen Minh Ngoc;Ong Winston Zapanta |
分类号 |
C07D491/107;A61K9/50;A61K31/517 |
主分类号 |
C07D491/107 |
代理机构 |
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代理人 |
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主权项 |
1. 7-(3-(4-(4-Fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxyquinazolin-7-yloxy)propyl)-2-oxa-7-azaspiro[3.5]nonane in crystalline Form B. |
地址 |
Waltham MA US |