METHODS OF TREATING A GASTROINTESTINAL SPASM ASSOCIATED WITH CHEMOTHERAPY OR RADIATION THERAPY

摘要

Methods of treating a gastrointestinal spasms associated with chemotherapy or radiation therapy are provided, such methods not requiring the use of systemic drugs that have shown to (i) provide slow relief, (ii) cause adverse side effects, (iii) limit activities, (iv) worsen existing gastrointestinal conditions, (v) be unrecommended in several gastrointestinal conditions that include gastrointestinal spasms, or (vi) be unrecommended in the absence of diarrhea.

主权项

1. A method of inhibiting the onset of, and treating, a gastrointestinal spasm associated with the administration of chemotherapy or radiation therapy in a subject, the method comprising:
administering an effective amount of a formulation to a subject to gastrointestinal spasm associated with the administration of chemotherapy or radiation therapy, the formulation having a water soluble tannin combined with hydrogen peroxide in a pharmaceutically acceptable excipient; wherein, the tannin has a molecular weight ranging from about 170 Daltons to about 4000 Daltons; the tannin:peroxide weight ratio ranges from about 1:1000 to about 10:1; and, the composition inhibits the onset of, and treats, a gastrointestinal spasm associated with chemotherapy or radiation therapy in the subject when compared to a second subject in a control group also exposed to the chemotherapy or radiation therapy in which the composition was not administered.