摘要 |
The present invention provides compositions and methods relating to or derived from antigen binding proteins to CHRDL-1. Human, humanized, and chimeric antibodies, as well as fragments and derivatives thereof are further contemplated where such antibodies are defined as selectively binding to CHRDL-1 in particular regions of the protein that result in neutralization and thereby treatment of disorders associated with CHRDL-1 expression. Other embodiments include nucleic acids encoding such antigen binding proteins, and fragments and derivatives thereof, as well as polypeptides, cells, methods of making and using antigen binding proteins, fragments and derivatives thereof. |