发明名称 |
PORCINE PSEUDORABIES VIRUS GENE DELETION STRAIN, VACCINE COMPOSITION, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF |
摘要 |
The present invention provides an attenuated strain of porcine pseudorabies virus (PRV), in which said attenuated strain of PRV is a variant strain of PRV with inactivation of gI/gE/11K/28K proteins. In addition, the present invention also provides a vaccine composition comprising the attenuated strain of PRV as an antigen, a preparation method and use thereof. Proved by immunogenicity and pathogenicity testing of the live vaccine, said live PRV vaccine can provide a good protection for pigs with no clinical signs observed, indicating excellent immune protection. |
申请公布号 |
EP3012322(A1) |
申请公布日期 |
2016.04.27 |
申请号 |
EP20150808317 |
申请日期 |
2015.01.06 |
申请人 |
PULIKE BIOLOGICAL ENGINEERING, INC. |
发明人 |
TIAN, KEGONG;ZHANG, XUKE;SUN, JINZHONG;TAN, FEIFEI |
分类号 |
C12N7/04;A61K39/12;A61K39/245;A61P31/22;C12R1/93 |
主分类号 |
C12N7/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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