发明名称 |
SINGLE AGENT ANTI-PD-L1 AND PD-L2 DUAL BINDING ANTIBODIES AND METHODS OF USE |
摘要 |
The present invention is based, in part, on the identification of novel antibodies that have binding affinity for both PD-L1 and PD-L2 and methods of using same. In one aspect, an isolated monoclonal antibody, or antigen-binding fragment thereof, which specifically binds both PD-L1 and PD-L2, is provided. In one embodiment, both PD-L1 and PD-L2 are human PD-L1 and human PD-L2. |
申请公布号 |
EP2890715(A4) |
申请公布日期 |
2016.04.27 |
申请号 |
EP20130824810 |
申请日期 |
2013.08.02 |
申请人 |
DANA-FARBER CANCER INSTITUTE, INC. |
发明人 |
FREEMAN, GORDON, J.;SHARPE, ARLENE, H. |
分类号 |
C07K16/28 |
主分类号 |
C07K16/28 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|