| 发明名称 |
VACCINIA VIRUS FOR GENE-DIRECTED ENZYME PRODRUG THERAPY |
| 摘要 |
Methods of making vaccinia viruses for gene-directed prodrug therapy are disclosed and their use in the treatment of disease is provided. In particular, the anti-tumor effects of vaccinia viruses that are modified to express a prodrug-activating enzyme are disclosed. |
| 申请公布号 |
EP3010518(A1) |
申请公布日期 |
2016.04.27 |
| 申请号 |
EP20140732604 |
申请日期 |
2014.06.18 |
| 申请人 |
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL |
发明人 |
MARAIS, RICHARD;SPRINGER, CAROLINE;TOMMASINI, SERENA |
| 分类号 |
A61K35/76;A61K31/135;A61K38/48;A61P35/00 |
主分类号 |
A61K35/76 |
| 代理机构 |
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