| 摘要 |
FIELD: medicine.SUBSTANCE: method relates to paediatric rheumatology, immunology and haematology and can be used for early diagnosis of severe life-threatening complication of systemic juvenile idiopathic arthritis (SJIA) - macrophage activation syndrome (MAS). Method comprises analysis of biochemical parameters of blood and urine. In presence of at least three values of following parameters: reduced number of platelets ≤211×109/l, reduced number of leukocytes ≤9.9×109/l, increased AST>59.7 E/l, increased LDG>882 E/l, reduced albumin ≤29 g/l, increased ferritin >400 mcg/l, reduced fibrinogen ≤1.8 g/l and the presence of proteinuria <1.0 g/24 hours, macrophage activation syndrome is diagnosed.EFFECT: using presented diagnostic technique enables early and highly accurate diagnosis of developing early macrophage activation syndrome with 100% sensitivity and specificity.1 cl, 3 ex |
