发明名称 STABILIZED CRYSTAL OF TIPIRACIL HYDROCHLORIDE, AND CRYSTALLIZATION METHOD FOR SAME
摘要 An objective of the present invention is to obtain a stable crystal form of 5-chloro-6-(2-iminopyrrolidin-1-yl)methyl-2,4(1H,3H)-pyrim idinedione hydrochloride. The present invention provides a crystal of 5-chloro-6-(2-iminopyrrolidin-1-yl)methyl-2,4(1H,3H)-pyrim idinedione hydrochloride exhibiting characteristic peaks at angles of 11.6°, 17.2°, 17.8°, 23.3°, 27.1°, and 29.3° as a diffraction angle (2¸ ± 0.1°) in powder X-ray diffraction.
申请公布号 EP3012255(A1) 申请公布日期 2016.04.27
申请号 EP20140814354 申请日期 2014.06.17
申请人 TAIHO PHARMACEUTICAL CO., LTD. 发明人 KAZUNO, HIDEKI;MUTSUMI, TOMONOBU
分类号 C07D403/06;A61K31/506;A61K31/7072;A61P35/00;A61P43/00 主分类号 C07D403/06
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