CAMELID SINGLE HEAVY-CHAIN ANTIBODY DIRECTED AGAINST CHROMATIN AND USES OF SAME

摘要

Disclosed is a polypeptide including a single-domain antibody directed against chromatin, derived from a heavy-chain antibody devoid of a camelid light chain (VHH) and capable of binding specifically with a complex of H2A and H2B histones. This polypeptide is particularly suitable for detecting/viewing chromatin in real time, without interfering with the rate of cell proliferation.