发明名称 |
Multiple sample chromatography using a stochastic injection technique |
摘要 |
The invention relates to a method for simultaneously analyzing at least two samples using a chromatography device comprising a chromatography column having an inlet and an outlet, and at least one detector placed at the outlet of the chromatography column, the method comprising steps of: injecting fractions of each independent sample at the inlet of the chromatography column, the fractions of each independent sample being injected according to a specific injection timing sequence derived from a pseudo-random binary sequence associated with said independent sample; recording a signal generated by said detector for a period of time at least equal to a duration of the longest of the specific injection timing sequences; cross-correlating the recorded signal and a derived correlation function, said derived correlation function being derived from the pseudo-random binary sequence associated with one of the independent samples, so as to obtain an individual correlogram signal specific to said independent sample; and analyzing data of interest of the individual correlogram signal so as to obtain an output signal indicative of a composition of the sample. |
申请公布号 |
US9322812(B2) |
申请公布日期 |
2016.04.26 |
申请号 |
US201414158130 |
申请日期 |
2014.01.17 |
申请人 |
Institut Francais des Sciences et Technologies des Transports, De L'Amenagement et des Reseaux (IFSTTAR);Chambre de Commerce et D'Industrie de Region Paris Ile de France (ESIEE Paris) |
发明人 |
Angelescu Dan;Cesar William;Bourouina Tarik |
分类号 |
G01N30/16;G01N30/86 |
主分类号 |
G01N30/16 |
代理机构 |
Lerner, David, Littenberg, Krumholz & Mentlik, LLP |
代理人 |
Lerner, David, Littenberg, Krumholz & Mentlik, LLP |
主权项 |
1. A method for simultaneously analyzing at least two samples using a chromatography device comprising a chromatography column having an inlet and an outlet, and at least one detector placed at the outlet of the chromatography column, the method comprising steps of:
injecting fractions of each independent sample at the inlet of the chromatography column, the fractions of each independent sample being injected according to a specific injection timing sequence derived from a pseudo-random binary sequence associated with said independent sample; recording a signal generated by said detector for a period of time at least equal to a duration of the longest of the specific injection timing sequences; cross-correlating the recorded signal and a derived correlation function, said derived correlation function being derived from the pseudo-random binary sequence associated with one of the independent samples, so as to obtain an individual correlogram signal specific to said independent sample; and analyzing data of interest of the individual correlogram signal so as to obtain an output signal indicative of a composition of the sample. |
地址 |
FR |