发明名称 Powderous formulations of organic acids or esters having an aromatic ring system
摘要 The present invention relates to improved powderous formulations of organic acids or esters having an aromatic ring system, as well as to the production of such formulations.
申请公布号 US9320688(B2) 申请公布日期 2016.04.26
申请号 US201314377027 申请日期 2013.02.06
申请人 DSM IP ASSETS B.V. 发明人 Gadient Martin;Lindemann Thomas;Voelker Karl Manfred;Urban Kai;Kirchen Stefanie;Keller Andreas
分类号 A61K9/14;A61K8/02;A61K9/16;A23L1/302;A23K1/16;A23L1/30;A23L3/3517;A61Q19/00 主分类号 A61K9/14
代理机构 Nixon & Vanderhye P.C. 代理人 Nixon & Vanderhye P.C.
主权项 1. A powderous formulation comprising (i) 0.5 to 60 wt-%, based on the total weight of the powderous formulation, of at least one compound of formula (I) whereinX is —N— or CH— andR1 is H or a C1-C4 alkyl moiety, and (ii) 0.5-50 wt-%, based on the total weight of the powderous formulation, of an auxiliary compound having an average particle size (d 0.5) in the powderous formulation of 10 μm to 100 μm, wherein the auxiliary compound is a least one selected from the group consisting of aluminum ammonium sulphate, aluminum potassium sulfate, ammonium acetate, ammonium bisulphite, ammonium carbonate, ammonium chloride, ammonium dihydrogen phosphate, ammonium hydrogen carbonate, bentonite, montmorillonite, calcium aluminates, calcium carbonate, calcium silicate, synthetic calcium sulphate dihydrate, calcium sulfate, kaolinitic clays, diatomaceous earth, perlite, potassium bisulphite, potassium hydrogen carbonate, potassium sulphate, potassium carbonate, sepiolitic clays, silicic acid, synthetic sodium aluminosilicate, sodium aluminosulfate, sodium bisulphate, sodium carbonate, sodium chloride, sodium hydrogen carbonate, sodium sulphate, vermiculite, calcium carbonate, magnesium carbonate, calcareous marine algae, magnesium oxide, magnesium sulphate, dicalcium phosphate, tri-calcium phosphate, mono-dicalcium phosphate, defluorinated rock-phosphate, monocalcium phosphate, calcium-magnesium phosphate, mono-ammonium phosphate, magnesium phosphate, sodium-calcium-magnesium phosphate, mono-sodium phosphate, glycerol, propylene glycol, glyceryl triacetate , sorbitol, polydextrose, lactic acid and urea, and (iii) up to 40 wt-%, based on the total weight of the powderous formulation, of a carrier material (iv)the formulation having MIE values of 10-1000 mJ.
地址 Heerlen NL