发明名称 | Acid addition salt of substituted pyridine compound | ||
摘要 | The present invention provides a salt of a substituted pyridine compound which has excellent CETP inhibition activity and is useful as a medicament. The present invention provides a salt of a compound represented by general formula (I):; wherein R1 is optionally substituted alkoxy or the like. | ||
申请公布号 | US9321747(B2) | 申请公布日期 | 2016.04.26 |
申请号 | US201314370634 | 申请日期 | 2013.01.04 |
申请人 | DAIICHI SANKYO COMPANY, LIMITED;UBE INDUSTRIES, LTD. | 发明人 | Kawai Yukinori;Iwase Noriaki;Kikuchi Osamu;Takata Katsunori;Motoyama Takahiro;Hagihara Masahiko |
分类号 | C07D401/14;C07C55/24;C07C55/08;C07C309/04 | 主分类号 | C07D401/14 |
代理机构 | Dorsey & Whitney LLP | 代理人 | Dorsey & Whitney LLP |
主权项 | 1. A salt formed from a compound of formula (I): wherein R1 is a (2S)-2,3-dihydroxypropyloxy group, a (2R)-2,3-dihydroxypropyloxy group, a 3-hydroxy-3-methylbutoxy group, a 3-(methylsulfonyl)propoxy group, a 3-hydroxy-2-(hydroxymethyl)propoxy group, a 3-hydroxy-2-(hydroxymethyl)-2-methylpropoxy group or a 3-carboxyphenyl group, and an acid selected from hydrochloric acid, hydrobromic acid, methanesulfonic acid, benzenesulfonic acid, succinic acid, fumaric acid and maleic acid. | ||
地址 | Tokyo JP |