发明名称 Acid addition salt of substituted pyridine compound
摘要 The present invention provides a salt of a substituted pyridine compound which has excellent CETP inhibition activity and is useful as a medicament. The present invention provides a salt of a compound represented by general formula (I):; wherein R1 is optionally substituted alkoxy or the like.
申请公布号 US9321747(B2) 申请公布日期 2016.04.26
申请号 US201314370634 申请日期 2013.01.04
申请人 DAIICHI SANKYO COMPANY, LIMITED;UBE INDUSTRIES, LTD. 发明人 Kawai Yukinori;Iwase Noriaki;Kikuchi Osamu;Takata Katsunori;Motoyama Takahiro;Hagihara Masahiko
分类号 C07D401/14;C07C55/24;C07C55/08;C07C309/04 主分类号 C07D401/14
代理机构 Dorsey & Whitney LLP 代理人 Dorsey & Whitney LLP
主权项 1. A salt formed from a compound of formula (I): wherein R1 is a (2S)-2,3-dihydroxypropyloxy group, a (2R)-2,3-dihydroxypropyloxy group, a 3-hydroxy-3-methylbutoxy group, a 3-(methylsulfonyl)propoxy group, a 3-hydroxy-2-(hydroxymethyl)propoxy group, a 3-hydroxy-2-(hydroxymethyl)-2-methylpropoxy group or a 3-carboxyphenyl group, and an acid selected from hydrochloric acid, hydrobromic acid, methanesulfonic acid, benzenesulfonic acid, succinic acid, fumaric acid and maleic acid.
地址 Tokyo JP
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