ANTHRACYCLINE DERIVATIVE CONJUGATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR COMPOUNDS
摘要
The present invention relates to conjugates of therapeutically useful anthracyclines with carriers such as polyclonal and monoclonal antibodies, proteins or peptides of natural or synthetic origin; methods for their preparation, pharmaceutical composition containing them and use thereof in treating certain mammalian tumors.
申请公布号
CA2727915(C)
申请公布日期
2016.04.26
申请号
CA20092727915
申请日期
2009.07.14
申请人
GENENTECH, INC.;NERVIANO MEDICAL SCIENCES S.R.L.
发明人
BERIA, ITALO;CARUSO, MICHELE;FLYGARE, JOHN A.;LUPI, VITTORIA;PEREGO, RITA;POLAKIS, PAUL;POLSON, ANDREW;SALSA, MATTEO;SPENCER, SUSAN D.;VALSASINA, BARBARA