| 发明名称 |
Ligand |
| 摘要 |
The invention provides a dual-specific ligand comprising a first immunoglobulin variable domain having a first binding specificity and a complementary or non-complementary immunoglobulin variable domain having a second binding specificity. |
| 申请公布号 |
US9321832(B2) |
申请公布日期 |
2016.04.26 |
| 申请号 |
US200711704832 |
申请日期 |
2007.02.08 |
| 申请人 |
Domantis Limited |
发明人 |
Tomlinson Ian;Jespers Laurent;Clube Jasper;Holt Lucy J.;Schon Oliver |
| 分类号 |
C12P21/08;C07K16/00;C07K17/00;C07K17/14;C07K16/18;C07K16/24;C07K16/28 |
主分类号 |
C12P21/08 |
| 代理机构 |
|
代理人 |
Fedon Jason C.;Han William T. |
| 主权项 |
1. An isolated ligand comprising an antibody single variable domain that has a binding site with binding specificity for Domain II of serum albumin, wherein said antibody single variable domain with binding specificity for Domain II of serum albumin comprises SEQ ID NO: 95 (CDR1), SEQ ID NO: 96 (CDR2) and SEQ ID NO: 97 (CDR3) of the amino acid sequence of SEQ ID NO: 235 (dAb7h14). |
| 地址 |
GB |
