| 主权项 |
1. A compound of formula I: wherein A1 represents —O—, —S— or —CH2—; A2 represents —CH2— or —O—; A3 represents C3-C8cycloalkylene; saturated or unsaturated 4 to 8-membered heterocyclodiyl with 1, 2 or 3 heteroatoms selected from nitrogen or oxygen, which group A3 is unsubstituted or substituted by one or more substituents each independently of the others being selected from fluorine, chlorine, bromine or iodine atoms, carboxy, alkyl, alkoxy, mono- or di(C1-C4alkyl)amino, OH, ═O, SH, ═S, NH2, ═NH, cyano, NO2, C1-C4alkoxycarbonyl, morpholinocarbonyl and hydroxyC1-C4alkyl groups; A4 represents C1-C4alkylene or —C(═O)—; G represents a group selected from pyrido[3,2-b][1,4]oxazine and benzo[1,4]oxazine which are unsubstituted or substituted by one or more substituents, each independently of the others being selected from fluorine, chlorine, bromine or iodine atoms, carboxy, alkyl, alkoxy, mono- or di(C1-C4alkyl)amino, OH, ═O, SH, ═S, NH2, ═NH cyano and NO2 groups and the pyrido or benzo part of the pyrido[3,2-b][1,4]oxazine and benzo[1,4]oxazine groups can also be substituted by C1-C4alkyl further substituted with fluoro; X1 represents a nitrogen atom or CR1; R1 represents a hydrogen atom or a halogen atom; R2 represents a hydrogen atom; m is 0 or 1; n is 1; the —(CH2)n— group is unsubstituted; p is 0 or 1; or a pharmaceutically acceptable salt thereof. |
