sal de ácido maleico de 2-[2-((s)-3-dimetilaminopirolidina-1-il)piridina-3-il]-5-etila-7-metoxi-4h-benz[d][1,3]oxazina-4-one; cristais de 2-[2-((s)-3-dimetilaminopirolidina-1-il)piridina-3-il)]-5-etila-7-metoxi-4h-benz[d][1,3]oxazina-4-one; maleato e monomaleato; misturas destes cristais, métodos para a produção e recristalização do cristal de 2-[2-((s)-3-dimetilaminopirolidina-1-il)piridina-3-il)]-5-etila-7-metoxi-4h-benz[d][1,3]oxazina-4-one; monomaleato e medicamento contendo este cristal

摘要

Disclosed is a benz[d][1,3]oxazine derivative having excellent stability when used as an active ingredient for a medicinal agent, and also having excellent solubility and crystallinity. Specifically disclosed is 2-[2-((S)-3-dimethylaminopyrrolidin-1-yl)pyridin-3-yl]-5-ethyl-7-methoxy-4H-benz [d][1,3]oxazin-4-one maleate.