| 发明名称 | Compositions and methods for modulating thrombin generation | ||
| 摘要 | Factor V peptides and methods of use thereof are disclosed. | ||
| 申请公布号 | US9321826(B2) | 申请公布日期 | 2016.04.26 |
| 申请号 | US201414250840 | 申请日期 | 2014.04.11 |
| 申请人 | The Children's Hospital of Philadelphia | 发明人 | Camire Rodney M.;Bunce Matthew W.;Bos Mettine H. A. |
| 分类号 | C07K14/745;A61K38/36;A61K45/06;A61K38/00 | 主分类号 | C07K14/745 |
| 代理机构 | Dann, Dorfman, Herrell & Skillman | 代理人 | Netter, Jr. Robert C.;Dann, Dorfman, Herrell & Skillman |
| 主权项 | 1. A method for inhibiting clot formation in a subject in need thereof, said method comprising administering to said subject at least one composition comprising at least one peptide having at least 80% homology with SEQ ID NO: 1, 2, 3, or 4 and at least one pharmaceutically acceptable carrier, wherein said peptide has a length of about 20 to about 80 amino acids. | ||
| 地址 | Philadelphia PA US | ||