发明名称 |
Derivados 2-aminopirimidina útiles como inhibidores de JNK |
摘要 |
Compounds of formula I or pharmaceutically acceptable salts thereof, wherein R5 is a group of formula (a) or (b): and wherein m, n, p, q, X, Y, R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as defined herein. The compounds and compositions disclosed herein are useful to modulate the activity of JNK and treat diseases associated with JNK activity. |
申请公布号 |
ES2567828(T3) |
申请公布日期 |
2016.04.26 |
申请号 |
ES20110723059T |
申请日期 |
2011.06.01 |
申请人 |
F. Hoffmann-La Roche AG |
发明人 |
ARZENO, Humberto;FILONOVA, Lubov;GOLDSTEIN, David;GONG, Leyi;LOE, Bradley;O'BRIEN, Erin;PALMER, Wylie;ROTSTEIN, David;SILVA, Tania;TAN, Yun-chou |
分类号 |
C07D401/04;A61K31/506;A61P3/10;A61P11/06;A61P19/02;A61P29/00;C07D401/14;C07D403/04;C07D403/14;C07D409/14;C07D487/02 |
主分类号 |
C07D401/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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