Process for manufacturing 3-alkyl-n-[4-(4-alkyl-piperazin-1-yl)-cyclohexyl]-4-nitro-benzamide and intermediates thereof

摘要

The present invention relates to an improved process for manufacturing dihydropteridinones of general formula (12) as well as intermediates thereof, wherein the groups R1, R2, R3, R4, and R5 have the meanings given in the claims and specification.