发明名称 |
Compositions and methods for the treatment of metabolic and body weight related disorders |
摘要 |
The present invention relates to compounds, pharmaceutical compositions and formulations that have a tripartite structure A-B-C having having a piperidinyl, a pyrrolinyl or pyridinyl A ring, a thiazole B ring, and a phenyl C ring which may be further substituted independently. Also provided are methods for treating a metabolic disorder or a cell hyperproliferative disease with the compounds, pharmaceutical compositions and formulations described herein. Further provided are methods for reducing body weight or increasing thermogenesis during weight loss with the compounds of structure A-B-C, as described, or of structure Formula where R |
申请公布号 |
AU2014312227(A1) |
申请公布日期 |
2016.04.21 |
申请号 |
AU20140312227 |
申请日期 |
2014.08.29 |
申请人 |
BAYLOR COLLEGE OF MEDICINE |
发明人 |
UESUGI, MOTONARI;WAKIL, SALIH J.;ABU-ELHEIGA, LUTFI;WATANABE, MIZUKI |
分类号 |
C07D417/04;A61K31/426;A61K31/4439;A61P3/00;C07D213/06;C07D231/06;C07D277/22;C07D277/24;C07D277/66;C07D417/14 |
主分类号 |
C07D417/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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