PEPTIDE DERIVED FROM TRKB-FL AND USE THEREOF AS A NEUROPROTECTOR

摘要

The invention relates to a neuroprotective peptide characterised in that it consists of 15 amino acids of the human TrkB-FL sequence corresponding to positions 458 to 472 of the canonical sequence, and can exert a neuroprotective effect when the pro-survival response time is increased. The invention also relates to the use of said peptide for preventing and/or treating neuronal damage in mammals caused by a pathology of the central nervous system associated with excitotoxicity. The invention further relates to a pharmaceutical composition characterised in that it comprises said neuroprotective peptide, and to the use of same in the treatment of cerebrovascular diseases and other pathologies of the CNS.