| 摘要 |
PROBLEM TO BE SOLVED: To provide a compound useful for treatment and/or prevention of sodium channel mediated diseases or conditions.SOLUTION: The invention relates to a spiro-oxindole compound represented by the formula (I), where k, j, Q, R, R, R, R, R, R, R, R, Rare as defined in the application, or a pharmaceutically acceptable salt, solvate or prodrug as a stereoisomer, an enantiomer, a tautomer of a mixture thereof, and these are useful for treatment and/or prevention of sodium channel mediated diseases or conditions such as pain. There is disclosed a pharmaceutical composition containing the compound, a method for manufacturing the compound and method of using the same.SELECTED DRAWING: None |
