发明名称 |
POLYMERIC DELIVERY FORMULATIONS OF LEUPROLIDE WITH IMPROVED EFFICACY |
摘要 |
The present invention is directed to a flowable composition that is suitable for use as a controlled release implant. The flowable composition includes a biodegradable thermoplastic polyester that is at least substantially insoluble in aqueous medium or body fluid. The flowable composition also includes a biocompatible polar aprotic solvent. The biocompatible polar aprotic solvent is miscible to dispersible in aqueous medium or body fluid. The flowable composition also includes leuprolide acetate. |
申请公布号 |
US2016106805(A1) |
申请公布日期 |
2016.04.21 |
申请号 |
US201514930387 |
申请日期 |
2015.11.02 |
申请人 |
Tolmar Therapeutics, Inc. |
发明人 |
Dunn Richard L.;Garrett John Steven;Ravivarapu Harish;Chandrashekar Bhagya L. |
分类号 |
A61K38/09;A61K9/00 |
主分类号 |
A61K38/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Fort Collins CO US |