Polymer/Copper Combination for Targeted Cancer Therapy

摘要

Polymer/copper combination that can selectively target and kill cancer cells are described. Materials can include the reaction product of a biocompatible hydrophilic polymer and pyridine-2-thiol containing monomer. The copolymer reaction product can include pyridine-2-thiol side groups pendant to the backbone via a disulfide linkage. The hydrophilic component can form the polymer backbone and/or can form hydrophilic pendant groups off of the backbone. Copper ions can be associated with the copolymer.

主权项

1. A polymer/copper combination comprising a biocompatible copolymer, the biocompatible copolymer including pyridine-2-thiol groups pendant to a backbone of the copolymer via a disulfide linkage, the biocompatible copolymer comprising a hydrophilic component, the polymer/copper combination further comprising copper ions