Amino acid surrogates for peptidic constructs

摘要

Ring-constrained amino acid surrogates of formula I where R¹, R², R³, R⁴, R⁵, R^6a, R^6b, R⁷, and y are as defined in the specification, methods for synthesizing ring-constrained amino acid surrogates of formula I, methods of use of ring-constrained amino acid surrogates of formula I, including use in linear or cyclic compounds which include a plurality of amino acid residues and one or more ring-constrained amino acid surrogates of formula I and linear or cyclic compounds which include a plurality of amino acid residues and one or more ring-constrained amino acid surrogates of formula I.