发明名称 |
PROTEASE-RESPONSIVE PEPTIDE BIOSENSORS AND METHODS FOR ANALYTE DETECTION |
摘要 |
The present invention relates to peptide biosensors comprising (a) a protease recognition site; (b) an analyte binding site; and (c) a signaling moiety that can produce a detectable signal upon cleavage of the protease recognition site by a protease. Further encompassed are detection reagents that comprise said peptide biosensors in combination with a protease and methods for detecting the presence of an analyte molecule or screening of candidate compounds that modulate the binding of an analyte to a binding partner of the analyte. |
申请公布号 |
US2016109438(A1) |
申请公布日期 |
2016.04.21 |
申请号 |
US201414895696 |
申请日期 |
2014.06.06 |
申请人 |
AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH |
发明人 |
Nirantar Saurabh Rajendra;Ghadessy Farid John |
分类号 |
G01N33/53;G01N33/68 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Singapore SG |