发明名称 |
Enteric Soft Capsules |
摘要 |
A gel mass is provided that is useful in manufacturing enteric soft or hard capsules, or enteric tablets without coating. |
申请公布号 |
US2016106682(A1) |
申请公布日期 |
2016.04.21 |
申请号 |
US201514978159 |
申请日期 |
2015.12.22 |
申请人 |
Banner Life Sciences LLC |
发明人 |
HASSAN EmadEldin M.;FATMI Aqeel A.;CHIDAMBARAM Nachiappan |
分类号 |
A61K9/48;A61K31/616;A61K31/4402;A61K31/5415;A61K31/663;A61K31/4439 |
主分类号 |
A61K9/48 |
代理机构 |
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代理人 |
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主权项 |
1. An enteric oral dosage form comprising an enteric soft capsule comprising a capsule shell encapsulating a fill, the capsule shell formed from a gel mass composition comprising:
(a) a gelatin, (b) an acid-insoluble polymer; (c) an alkaline aqueous solvent; and (d) one or more plasticizers; wherein a weight ratio range of the acid-insoluble polymer to the gelatin in the gel mass composition is from about 30% to about 40%; a weight ratio of a combined weight of the plasticizers to a combined weight of the gelatin and the acid-insoluble polymer in the gel mass composition is about 1:2; and a final pH of the gel mass composition is less than or equal to about 9 pH units. |
地址 |
High Point NC US |