PHARMACEUTICAL COMPOSITION AND USES THEREOF

摘要

The present invention relates to pharmaceutical compositions comprising fixed dose combinations of a DPP-4 inhibitor drug and metformin XR (extended release), processes for the preparation thereof, and their use to treat certain diseases.

主权项

1. A pharmaceutical composition comprising
a) an extended release core comprising metformin or metformin hydrochloride and one or more excipients; b) a barrier coating; and c) an immediate release coating comprising a DPP-4 inhibitor and one or more excipients; wherein the barrier coating comprises: one or more film-coating agents, an optional plasticizer, and optionally, a glidant, and/or an anti-tacking agent, and/or a pigment, and wherein the barrier coating is free of polydextrose.