发明名称 |
CELL POPULATIONS, METHODS OF TRANSDIFFERENTION AND METHODS OF USE THEREOF |
摘要 |
The present invention provides methods for the sequential and temporally-regulated administration of pancreatic transcription factors to induce non-pancreatic cells to transdifferentiate and mature along the pancreatic &bgr;-cell lineage. The present invention also provides methods for identifying, isolating and enriching transdifferentiation predisposed cells and methods for treating a degenerative pancreatic disorder such as diabetes. |
申请公布号 |
EP3007710(A2) |
申请公布日期 |
2016.04.20 |
申请号 |
EP20140818254 |
申请日期 |
2014.06.13 |
申请人 |
ORGENESIS LTD.;TEL HASHOMER - MEDICAL RESEARCH, INFRASTRUCTURE AND SERVICES LTD. |
发明人 |
FERBER, SARAH |
分类号 |
C12N5/071;A61K35/39;A61P5/48 |
主分类号 |
C12N5/071 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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