发明名称 二環式化合物およびその医薬用途
摘要 Provided is a compound which has strong intraocular pressure lowering action and has no side effect on eyes such as ocular stimulating property, humor protein rise etc. Since a compound represented by the formula (I): (wherein definition of each group is as described in the specification), or a salt thereof, a solvate thereof, or a prodrug thereof has strong intraocular pressure lowering activity and, further, has no side effect on eyes such as ocular stimulating property (hyperemia, corneal clouding etc.), aqueous humor protein rise etc., it has high safety, and can be an excellent agent for preventing and/or treating glaucoma etc.
申请公布号 JP5907077(B2) 申请公布日期 2016.04.20
申请号 JP20120554849 申请日期 2012.01.26
申请人 小野薬品工業株式会社 发明人 丸山 透;神戸 透;山根 晋作;中山 仁志
分类号 C07D335/04;A61K31/559;A61P27/02;A61P27/06;A61P27/10;A61P27/12;A61P43/00 主分类号 C07D335/04
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