发明名称 COMBINATIONS OF PHOSPHOINOSITIDE 3-KINASE INHIBITOR COMPOUNDS AND CHEMOTHERAPEUTIC AGENTS, AND METHODS OF USE.
摘要 Combinations of PI3K inhibitor compounds having Formulas (I) and (II) and chemotherapeutic agents, including stereoisomers, geometric isomers, tautomers, metabolites and pharmaceutically acceptable salts thereof, are useful for treating hyperproliferative disorders such as cancer. Methods of using such combinations for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
申请公布号 MX338504(B) 申请公布日期 2016.04.20
申请号 MX20100002543 申请日期 2008.09.10
申请人 GENENTECH, INC.* 发明人 MARCIA BELVIN;LORI FRIEDMAN;KLAUS HOEFLICH;DEEPAK SAMPATH;ULKA VIJAPURKAR;JEFFREY WALLIN;LEISA JOHNSON;MALLIKA SINGH;SONAL PATEL
分类号 A61K31/505;A61P35/00 主分类号 A61K31/505
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