发明名称 ミネラルコルチコイド受容体拮抗剤として使用のための縮合環化合物
摘要 The present invention belongs to the technical field of medicine, relating in particular to: a fused ring compound as represented by Formula (I) for use as a mineralocorticoid receptor antagonist, a pharmaceutically acceptable salt thereof, and an isomer thereof; a preparation method for these compounds; a pharmaceutical preparation containing these compounds; and an application of these compounds, the pharmaceutically acceptable salt thereof, or the isomers thereof in the preparation of medicants for the treatment and/or prevention of kidney injury, cardiovascular diseases such as hypertension, and/or endocrine disease. The definitions of X, Y 1 , Y 2 , Y 3 , R 1 , R 2a ,R 2b , R 3a , R 3b , R 4 , Cy and n are as presented in the description.
申请公布号 JP5906241(B2) 申请公布日期 2016.04.20
申请号 JP20130524336 申请日期 2011.08.18
申请人 山東亨利醫藥科技有限責任公司 发明人 黄振華;王金遠;張徳東
分类号 C07D471/04;A61K31/437;A61K31/4545;A61K31/496;A61K31/5377;A61K31/541;A61K45/00;A61P5/00;A61P9/00;A61P9/04;A61P9/06;A61P9/10;A61P9/12;A61P13/12 主分类号 C07D471/04
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