| 摘要 |
Interfaces suitable for connecting chromatography systems and mass spectrometers comprising, an ion source 112 including a first conduit 114 suitable for receiving eluent from a chromatography device, a heater 116 suitable for heating at least a portion of said first conduit, a second conduit 118 in fluid communication with the first conduit, an inlet 120 suitable for receiving eluent from said second conduit and introducing the eluent into an ion source region to form a plume of gas and/or liquid in the ion source region, and an ionization promoting inlet 124 suitable for injecting an ionization promoting fluid into the ion source region to interact with the plume to promote ionization of at least some of the plume. The ion source may be an electrospray ion source, an impactor spray ion source or an APCI ion source. The ion source may comprise a temperature or pressure sensor and feedback loop system for maintaining the temperature or pressure of the eluent. |
