IMPLANTABLE MATERIAL GRAFTED WITH A CELL ANTIPROLIFERATIVE AND/OR ANTIBACTERIAL FILM SYNTHETIZED FROM A BIFUNCTIONAL MOLECULE
摘要
The present invention relates to an implantable material having at least one external surface grafted with a film comprising carboxylate and sulfonate functions wherein the film is simultaneously synthesized and grafted directly on said external surface by radical reaction of a bifunctional adhesion primer of Formula (I) or by radical reaction of an adhesion primer and a bifunctional polymerizable monomer of Formula (II). The invention also relates to a process for directly synthesizing and grafting of a film according to the invention onto at least one external surface of an implantable material. The invention further relates to the use of a grafted implantable material for the manufacture of an antiproliferative and/or antibacterial implantable medical device. The invention also relates to compounds of Formula (I) and Formula (II).
申请公布号
EP3007738(A1)
申请公布日期
2016.04.20
申请号
EP20140736304
申请日期
2014.06.13
申请人
BIOWINTECH;COMMISSARIAT À L'ENERGIE ATOMIQUE ET AUX ENERGIESALTERNATIVES