| 发明名称 |
BIOLOGICAL MICROCHIP WITH PRIMER SET FOR ANALYSIS OF POLYMORPHISM IN AB0, HLA-DQA1, AMEL, DARC, NAT2 GENES |
| 摘要 |
FIELD: biochemistry.SUBSTANCE: invention relates to the field of biochemistry. Disclosed is set of differentiating oligonucleotides for analysis of polymorphism in genes AB0, HLA-DQA1, AMEL, DARC, NAT2 using hydrogel DNA-microchips (biochips). Biochip enables detecting nucleotide composition in fourteen polymorphous positions that in turn enables to establish genotype in said genes. Also disclosed is set of PCR primers for amplifying said loci.EFFECT: invention increases discriminatory potential of biochip (36,450 genotype groups).3 cl, 3 dwg, 3 tbl, 4 ex |
| 申请公布号 |
RU2582216(C2) |
申请公布日期 |
2016.04.20 |
| 申请号 |
RU20140109638 |
申请日期 |
2014.03.13 |
| 申请人 |
FEDERALNOE GOSUDARSTVENNOE BJUDZHETNOE UCHREZHDENIE NAUKI ROSSIJSKOJ AKADEMII NAUK INSTITUT MOLEKULJARNOJ BIOLOGII IM. V.A. ENGELGARDTA ROSSIJSKOJ AKADEMII NAUK (IMB RAN) |
发明人 |
FESENKO DENIS OLEGOVICH;KORNIENKO ALEKSANDRA EVGENEVNA;NASEDKINA TATJANA VASILEVNA;ZASEDATELEV ALEKSANDR SERGEEVICH |
| 分类号 |
C12N15/00;C12Q1/68 |
主分类号 |
C12N15/00 |
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