TRANSDERMAL AGENT FOR TREATING AND PREVENTING JOINT AND SOFT TISSUE DISEASES, METHOD FOR PRODUCTION THEREOF AND COMBINED TRANSDERMAL PREPARATION FOR TREATING AND PREVENTING JOINT AND SOFT TISSUE DISEASES

摘要

FIELD: medicine.SUBSTANCE: invention relates to medicine and provides transdermal agent for treating and preventing joint and soft tissue diseases. Agent contains glucosamine cartilage protector; non-steroid anti-inflammatory drug ketoprofen; pharmaceutically acceptable base containing a mixture of solvent N-methylpyrrolidone and propylene glycol; antioxidant for cartilage protector, specifically lidocaine and citric acid; gelling agent, capable of forming gels in an acidic medium, and an emulsifier in form of a nonionic surfactant. Acidity varies from pH 2.9 to 2.2. Invention also relates to a method of producing a transdermal agent.EFFECT: technical result consists is a wider range of products, high stability, high degree of transdermal penetration of active component and minimal side effects.12 cl, 1 dwg, 6 tbl