Method for mass spectrometry analysis and compounds useful therefor

摘要

The application relates to a method for mass spectrometry analysis of components in a sample whereby said components are labeled with a mass tag. Said mass tags are compounds capable of generating aromatic ions containing 4n+2 electrons in a closed ring system whereby the method for mass spectrometry includes detecting by mass spectrometry of aromatic ions containing 4n+2 electrons in the closed ring system whereby the charge is located within the aromatic system. In preferred embodiments, the tags comprise triaryl-cyclopropenium and substituted dibenzo-cycloheptatrienyl (tropyl) carbonium ions. A kit of reagents comprising such mass tags is also disclosed.