发明名称 |
ANTI-MIR-27B AND ANTI-MIR-148A OLIGONUCLEOTIDES AS THERAPEUTIC TOOLS FOR TREATING DYSLIPIDEMIAS AND CARDIOVASCULAR DISEASES |
摘要 |
The present invention relates to anti-miR-27b and anti-miR-148a oligonucleotides that are capable of decreasing the level and/or activity of miR-27b and miR-148a, respectively. In conjunction with the oligonucleotide molecules of the present invention, the invention also provides a method for decreasing the level and/or activity of miR-27b and/or miR-148a in a cell. In a further embodiment, the invention provides a method for treating a disease, especially dyslipidemias and cardiovascular diseases. |
申请公布号 |
EP3007706(A1) |
申请公布日期 |
2016.04.20 |
申请号 |
EP20140811385 |
申请日期 |
2014.06.12 |
申请人 |
NEW YORK UNIVERSITY |
发明人 |
FERNANDEZ-HERNANDO, CARLOS;GOEDEKE, LEIGH |
分类号 |
C12N15/113;A61K31/7105;A61P3/00;A61P9/00 |
主分类号 |
C12N15/113 |
代理机构 |
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