| 发明名称 | E2F as a target of hormone refractory prostate cancer | ||
| 摘要 | The instant invention provides amino acid sequences competing with E2F for DNA binding. Methods of using said amino acid sequences for treatment of hormone-refractory prostate cancer are also provided. | ||
| 申请公布号 | US9314497(B2) | 申请公布日期 | 2016.04.19 |
| 申请号 | US201414474595 | 申请日期 | 2014.09.02 |
| 申请人 | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 发明人 | Bertino Joseph R.;Banerjee Debabrata;Minko Tamara;Garbuzenko Olga B.;Xie Xiaoqi;Kerrigan John E.;Abali Emine E.;Scotto Kathleen W. |
| 分类号 | A61K38/08;A61K9/127;A61K38/16;A61K31/4436;A61K31/513;A61K31/519;A61K45/06;C07K14/47 | 主分类号 | A61K38/08 |
| 代理机构 | Fox Rothschild LLP | 代理人 | Fox Rothschild LLP |
| 主权项 | 1. A method of treating a patient diagnosed with a blood cancer expressing E2F-1 comprising administering to the patient a peptide having an amino acid sequence consisting essentially of RQIKIWFQNRRIKWKKHHHRLSH (SEQ ID NO: 34). | ||
| 地址 | New Brunswick NJ US | ||