| 发明名称 | Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid | ||
| 摘要 | The present invention relates to a substantially a solid form of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid (Compound 1, Solvate Form A and Compound 1, HCl Salt Form A), processes for making such forms, pharmaceutical compositions thereof, and methods of treatment therewith. | ||
| 申请公布号 | US9314455(B2) | 申请公布日期 | 2016.04.19 |
| 申请号 | US201514601608 | 申请日期 | 2015.01.21 |
| 申请人 | Vertex Pharmaceuticals Incorporated | 发明人 | Keshavarz-Shokri Ali;Zhang Beili;Krawiec Mariusz |
| 分类号 | A61K31/44;C07D405/00;A61K31/443;C07D213/75;C07D405/12;C07D405/14;A61K31/47;A61K45/06;C07D407/12 | 主分类号 | A61K31/44 |
| 代理机构 | Finnegan, Henderson, Farabow, Garrett & Dunner, LLP | 代理人 | Finnegan, Henderson, Farabow, Garrett & Dunner, LLP |
| 主权项 | 1. A solid form of 3-(6-(I-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid (Compound 1), characterized as Compound 1, Solvate Form A. | ||
| 地址 | Boston MA US | ||