Method and apparatus for fractional flow reserve measurements

摘要

A method of determining fractional flow reserve (FFR) in a blood vessel having stenosis includes injecting fluid into the blood vessel upstream of the stenosis using a power fluid injector, measuring pressure drop across the stenosis, and calculating FFR from measured pressure drop. The injected fluid may comprise a contrast medium. Further actions may include placing a pressure sensor proximal of the stenosis, injecting fluid into the blood vessel upstream of the stenosis using the power fluid injector, and measuring pressure in the blood vessel proximal of the stenosis. The pressure sensor may then be repositioned to a position distal of the stenosis, fluid may be reinjected into the blood vessel upstream of the stenosis using the power fluid injector, and pressure may be measured in the blood vessel distal of the stenosis.

主权项

1. A method of determining fractional flow reserve (FFR) in a blood vessel having stenosis comprising:
placing a pressure sensor proximal of the stenosis; injecting fluid with a fluid delivery system into the blood vessel proximal of the stenosis using a power fluid injector to identify a flow rate through the blood vessel; measuring pressure in the blood vessel proximal of the stenosis during injection of the fluid with the fluid delivery system; measuring pressure drop across the stenosis with the fluid delivery system based on the flow rate during injecting of the fluid with the power fluid injector; and calculating FFR from the measured pressure drop with the fluid delivery system, wherein injecting fluid into the blood vessel is reduced or discontinued when retrograde flow is present in the blood vessel.