主权项 |
1. A rapidly dispersible solid dosage form comprising a porous non-compressed three-dimensionally printed bound matrix comprising:
drug-containing particles having an average, median or mean effective particle size and comprising a first grade of oxcarbazepine (OXC) particles having an average, median or mean first native particle size, a second grade of OXC particles having an average, median or mean second native particle size, at least one disintegrant, at least one surfactant, and at least one binder; at least one disintegrant; and at least one binder; wherein the dosage form disperses in 15 sec or less when placed in 15 ml of aqueous fluid; and the ratio of average, median or mean effective particle size to average, median or mean, respectively, first native particle size ranges from a ratio that is greater than 1:1 to the ratio 5:1, and the ratio of average, median or mean effective particle size to average, median or mean respectively, second native particle size is 20:1 to 50:1. |