Mutation detection probe, mutation detection method, method of evaluating drug efficacy, and mutation detection kit

摘要

The present invention provides a probe for detecting a mutation in the ALK gene, which is at least one fluorescently labeled oligonucleotide selected from the group consisting of P1 to P4, P7 and P8 oligonucleotides; an application thereof; and an oligonucleotide for the application.

主权项

1. A mutation detection probe comprising a fluorescent dye and an oligonucleotide,
wherein the oligonucleotide consists of an oligonucleotide selected from the group consisting of SEQ ID NO: 5, 6, 7, 9 and 10, and the nucleotide bases at the first position from the 3′ end of SEQ ID NO: 5, 6 and 10, and at the first position from the 5′ end of SEQ ID NO: 7 and 9 are labeled with the fluorescent dye.