Device to measure pupillary light reflex in infants and toddlers

摘要

The present disclosure provides a pupillary light reflex (PLR) system, wherein the PLR system includes a remote tracking and imaging system that is structured and operable to generate and acquire high resolution pupil stimulus and response data from a test subject while the test subject is moving and is disposed a distance from remote tracking and imaging system that is greater than or equal to one-third of a meter. The PLR system additionally includes a computer based system controller that is structure and operable to execute PLR software to control the operation of the remote tracking and imaging system and compute PLR information based on the pupil stimulus and response data acquired as the test subject is moving.

主权项

1. A pupillary light reflex system, said system comprising:
a remote tracking and imaging system that is structured and operable to generate and acquire high resolution pupil stimulus and response data from a test subject while the test subject's head is moving and the test subject is disposed a distance from the remote tracking and imaging system that is at least one-third of a meter, wherein the remote tracking and imaging system comprises:
a subject movement tracking camera structured and operable to continuously track 3-dimensional and rotational movement of the test subject's head within a field of view of the subject movement tracking camera to acquire subject eye location data regarding movement of a location of the subject's eyes within a field of view of the subject movement tracking camera;an optical stimulation device structured and operable to generate light that causes a pupillary response of the test subject's eyes; andat least one pupil data acquisition camera structured and operable to acquire the high-resolution pupillary stimulus and response data; and a computer based system controller that is structure and operable to execute pupillary light reflex (PLR) software to control the operation of the remote tracking and imaging system and compute PLR information based on the pupil stimulus and response data acquired as the test subject is moving, and to correct a measured pupil size based on the subject's head position, orientation and eye gaze direction.