发明名称 AMORPHOUS FORM OF HETEROCYCLIC COMPOUND, SOLID DISPERSION AND PHARMACEUTICAL PREPARATION EACH COMPRISING THE SAME, AND PROCESS FOR PRODUCTION OF THE SAME
摘要 [PROBLEMS] The object is to improve the absorbability of a heterocyclic compound including s-triazine and a pyrimidine derivative in vitro. [MEANS FOR SOLVING PROBLEMS] Disclosed is, for example, an amorphous form of a heterocyclic compound as represented by the general formula (I) [wherein each of R's and others is as defined in the description] including s-triazine and a pyrimidine derivative, or a hydrate, a solvate or a pharmaceutically acceptable salt of the heterocyclic compound. Also disclosed is a process for producing the amorphous form. Further disclosed are: a solid dispersion comprising the amorphous body; and a medicinal preparation comprising the solid dispersion. (see formula I)
申请公布号 CA2706536(C) 申请公布日期 2016.04.19
申请号 CA20082706536 申请日期 2008.11.21
申请人 ZENYAKU KOGYO KABUSHIKIKAISHA 发明人 SUGAMA, TADAAKI;ISHIHARA, NOBUHIRO;TANAKA, YOSHIHARU;TAKAHASHI, MASAYUKI;YAGUCHI, SHINICHI;WATANABE, TETSUO
分类号 C07D403/04;A61K9/10;A61K9/14;A61K9/20;A61K9/48;A61K31/5377;A61K31/54;A61K47/38;A61P1/04;A61P1/06;A61P1/18;A61P11/00;A61P11/02;A61P11/06;A61P13/12;A61P17/00;A61P17/04;A61P17/06;A61P19/02;A61P19/08;A61P27/00;A61P27/02;A61P29/00;A61P31/04;A61P35/00;A61P35/02;A61P37/00;A61P37/02;A61P37/08;C07D413/14 主分类号 C07D403/04
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