| 发明名称 | Composition comprising a mixture of CD95-Fc isoforms and methods of producing same | ||
| 摘要 | The present invention relates to a composition comprising a mixture of fusion protein isoforms, each fusion protein comprising an extracellular CD95 domain or a functional fragment thereof or an Fc domain or functional fragment thereof, formulations providing such composition in a stable form as well as a method for producing such a composition. | ||
| 申请公布号 | US9315570(B2) | 申请公布日期 | 2016.04.19 |
| 申请号 | US201314415866 | 申请日期 | 2013.07.18 |
| 申请人 | APOGENIX GMBH | 发明人 | Hill Oliver;Gieffers Christian;Thiemann Meinolf |
| 分类号 | C07K16/18;C07K14/705;C07K7/08;C07K16/00;C07K14/525 | 主分类号 | C07K16/18 |
| 代理机构 | Perkins Coie LLP | 代理人 | Perkins Coie LLP ;Kung Viola T. |
| 主权项 | 1. A composition comprising a mixture of fusion protein isoforms, each fusion protein comprising at least an extracellular CD95 domain or a functional fragment thereof and at least a Fc domain or a functional fragment thereof distributing within a pI range of 4.0-8.5, wherein the mixture inhibits apoptosis. | ||
| 地址 | Heidelberg DE | ||