Bicyclic heteroaryl cycloalkyldiamine derivatives

摘要

The present invention relates to bicyclic heteroaryl cycloalkyldiamine derivatives, to processes for their production, to their use as SYK inhibitors and to pharmaceutical compositions comprising them. Formula (I);

主权项

1. A compound of the formula (I) or a pharmaceutically acceptable salt thereof, wherein X1 is CR1; X2 is CH; Y is CH2 or O; A is bicyclic hetereoaryl having from 8 to 10 ring atoms, wherein 1-3 of said ring atoms are heteroatoms selected from N, O and S and wherein said heteroaryl may be unsubstituted of substituted at a carbon atom by a R2 or at a nitrogen atom by a R3; R1 is H, Hal or C1-4 alkyl; R2 is H, C1-4 alkyl, C3-5 cycloalkyl, CN or Hal; and R3 is H or alkyl.