| 发明名称 |
METHOD FOR DETERMINING THE AMOUNT OF CONJUGATED TAXANE IN POLYGLUTAMIC ACID-TAXANE CONJUGATES |
| 摘要 |
The invention relates to a method for determining the amount of conjugated taxane, in particular paclitaxel, in a PGA-taxane conjugate said method comprising: a) reacting the PGA-taxane conjugate with a compound formula (I): R1R2N-NH2 (I), wherein R1 and R2 are as defined in the description; to give a unbound taxane and a PGA hydrazide and b) determining the amount of unbound taxane. |
| 申请公布号 |
CA2680073(C) |
申请公布日期 |
2016.04.19 |
| 申请号 |
CA20082680073 |
申请日期 |
2008.03.05 |
| 申请人 |
CELL THERAPEUTICS, INC. |
发明人 |
FAZIONI, STEFANO;HOVDA, KEITH;LIVI, VALERIA;MCKENNON, MARC;SIVIERO, LUIGI;SPOONEMORE, HOLLY |
| 分类号 |
G01N33/50 |
主分类号 |
G01N33/50 |
| 代理机构 |
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| 主权项 |
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